Jump to Content

Custom Login

Create New User Account or Login



Suggest new feature
  • Home
  • Analysis Tools
  • NeutBench
  • Blast
  • Stats
  • Structures
  • 1D - 3D
  • Biologist View
  • Downloads
  • Submit bNAb
  • Help
    • Links
      • Help
        • Use Cases
          • Supplementary Online Material
            • Publications
              • About Database
                • Slides for Presentations
                  • Videos
    close this panel

Biologist View

  • What is the proposed germline of a bNAb?
  • What are bNAb sequence characteristics?
    • Heavy Chain
    • Light Chain
  • Neutralization IC50 of bNAb X with virus isolate Y
  • Neutralizing activity of multiple bNAb against selected HIV isolate or subtype
  • Residues important for neutralization by bNAb
  • Neutralizing activity of bNAb against a panel of JR-CSF alanine mutants
  • bNAb structure solved
  • HIV-1 isolates sequences (LANL HIV sequence database)
  • Neutralization IC50 profile for bNAb(s)
  • Median ICs and percent viruses neutralized with an IC50 < 50 μg/ml
    • Median IC50 (μg/ml) against viruses neutralized with an IC50 < 50 μg/ml
    • Percent viruses neutralized with an IC50 < 50 μg/ml
    • Median IC50 (μg/ml) against all viruses
  • Competition of bNAb with sCD4 and bNAb in ELISA
  • Summary of Best Neutralizing Antibodies from LANL HIV Database
www.bNAber.org | 2013 | | A member of | Page accessed on August 17, 2018, 10:10 PM | Contact Us
bNAber is a database, analysis, visualization, and data discovery tool for broadly neutralizing HIV-1 antibodies (bNAbs), and seeks to be a vital tool in the search for an AIDS vaccine.