All bNAb

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NameDonorBinding SiteNeutralization breadth at IC50 < 50 μg/ml, %*Neutralization breadth at IC80 < 50 μg/ml, %**Neutralization potency (in μg/ml)Reference (s)PDB structure(s)
10-1074Donor 17V3 glycan5756 NA23115339 4FQ2
10E8N152gp41 MPER98 NA0.2523151583 4G6F
12A12Patient 12CD4bs100950.0621764753NA
12A21Patient 12CD4bs87 NA NA21764753 4JPW
2F5unknowngp41 MPER67431.447520721 3MOA 3MOB 3MOD 3LEV 3IDG 3IDI 3IDJ 3IDM 3IDN 3EGS 3DRT 3BQU 3D0L 3DRQ 3D0V 3DRO 2PW1 2PW2 2P8L 2P8M 2P8P 2PR4 1TJG 1TJH 1TJI 1U8H 1U8I 1U8J 1U8O 1U8P 1U8Q 1U91 1U92 2F5A 1U95 1U8M
2G12unknownothers41212.38 7520721 1ZLS 1ZLU 1ZLV 1ZLW 2OQJ 3OAU 3OAY 3OAZ 3OB0
35022N152face of contiguous areas of gp41 and gp12062 NA NA25186731 4TOY
3BC176Patient 3BCD4i/V3 NA NA NA22826297NA
3BNC117Patient 3CD4bs100950.0621764753 4JPV 4LSV
3BNC55Patient 3others81760.5221764753NA
3BNC60Patient 3CD4bs100 NA NA21764753 3RPI 4GW4
3BNC62Patient 3others73 NA NA21764753NA
447-52DunknownV3 glycan NA NA NA20098712 3C2A 1Q1J 3GHB 4M1D
4E10unknowngp41 MPER98363.417520721 1TZG 2FX9 2FX8 2FX7 3H3P
5H/I1-BMV-D5scFv-expressing phage-display librarygp41 MPER47 NA NA16203977 2CMR
8ANC195Patient 8others57570.8521764753NA
b12unknownCD4bs70 NA2.82 20616233 2NY7 3RU8
CAP256-VRC26.01CAP256V1/V21.88 NA NA24590074 4OCR
CAP256-VRC26.02CAP256V1/V20.4 NA NA24590074NA
CAP256-VRC26.03CAP256V1/V20.08 NA NA24590074 4OD1
CAP256-VRC26.04CAP256V1/V20.32 NA NA24590074NA
CAP256-VRC26.05CAP256V1/V20.1 NA NA24590074NA
CAP256-VRC26.06CAP256V1/V20.3812 NA24590074 4OCW
CAP256-VRC26.07CAP256V1/V21.51 NA NA24590074NA
CAP256-VRC26.08CAP256V1/V20.1147 NA24590074NA
CAP256-VRC26.09CAP256V1/V20.07 NA NA24590074NA
CAP256-VRC26.10CAP256V1/V20.6 NA NA24590074NA
CAP256-VRC26.11CAP256V1/V20.94 NA NA24590074NA
CAP256-VRC26.12CAP256V1/V20.49 NA NA24590074NA
CH01Subject CH0219V1/V246 NA NA21795340NA
CH02Subject CH0219V1/V236 NA NA21795340NA
CH03Subject CH0219V1/V245 NA NA21795340NA
CH04Subject CH0219V1/V245 NA NA21795340 3TCL 3U46 3U4B
CH103CH505CD4bs55 NA0.1823552890 4JAN 4JAM
HGN194VI 3265V3 glycan0.02 NA NA20098712NA
HJ16VI 3208CD4bs36 NA NA20098712NA
HK20VI 3081gp41 MPER0.4 - 8.8 NA NA20098712NA
M66.6SC44gp41 MPER31 NA22.2521880764NA
NIH45-46Donor 45CD4bs1001000.0721764753 3U7Y 3U7W
PCDN-33APC76N332 glycan supersite NA NA NA27192579NA
PCDN-33BPC76N332 glycan supersite NA NA NA27192579NA
PCDN-38APC76N332 glycan supersite NA NA NA27192579NA
PG16Protocol G African donor 24V1/V274 NA0.0219729618 3LRS 3MME 3MUG 4DQO
PG9Protocol G African donor 24V1/V279510.23 19729618 3U36 3U2S 3MUH 3U4E
PGDM1400Donor 84NA0.0030.003 NA2147483647 4RQQ
PGDM1401Donor 84NA0.0050.005 NA25422458NA
PGDM1402Donor 84NA NA NA NA25422458NA
PGDM1403Donor 84NA0.0410.041 NA25422458NA
PGDM1404Donor 84NA0.0440.044 NA25422458NA
PGDM1405Donor 84NA0.0060.006 NA25422458NA
PGDM1406Donor 84NA0.1730.173 NA25422458NA
PGDM1407Donor 84NA NA NA NA25422458NA
PGDM1408Donor 84NA NA NA NA25422458NA
PGDM1409Donor 84NA NA NA NA25422458NA
PGDM1410Donor 84NA NA NA NA25422458NA
PGDM1411Donor 84NA NA NA NA25422458NA
PGDM1412Donor 84NA NA NA NA25422458NA
PGT121Donor 17V3 glycan70550.03 21849977 4FQ1 4FQC 4JY4
PGT122Donor 17V3 glycan65540.05 21849977 4JY5 4NCO
PGT123Donor 17V3 glycan67520.03 21849977 4JY6
PGT125Donor 36V3 glycan52370.04 21849977NA
PGT126Donor 36V3 glycan60450.04 21849977NA
PGT127Donor 36V3 glycan50360.08 21849977 3TWC
PGT128Donor 36V3 glycan72570.02 21849977 3TV3 3TYG
PGT130Donor 36V3 glycan52280.16 21849977NA
PGT131Donor 36V3 glycan40190.52 21849977NA
PGT135Donor 39V3 glycan33170.17 21849977 4JM2 4JM4
PGT136Donor 39V3 glycan1657.81 23024643NA
PGT137Donor 39V3 glycan2273.46 23024643NA
PGT141Donor 84V1/V256350.35 21849977NA
PGT142Donor 84V1/V257400.21 21849977NA
PGT143Donor 84V1/V256330.31 21849977NA
PGT144Donor 84V1/V238142.06 21849977NA
PGT145Donor 84V1/V278530.29 21849977 3U1S
PGT151Donor 31gp41 and gp120 interface residues and glycans6644 NA24768347 4NUG
PGT152Donor 31gp41 and gp120 interface residues and glycans6447 NA24768347 4NUJ
VRC-CH30Donor 0219CD4bs8580 NA21835983NA
VRC-CH31Donor 0219CD4bs84 NA0.1421835983 4LSP 4LSQ 4LSR
VRC-CH32Donor 0219CD4bs8075 NA21835983NA
VRC-CH33Donor 0219CD4bs9080 NA21835983NA
VRC-CH34Donor 0219CD4bs8075 NA21835983NA
VRC-PG04Donor 74CD4bs76740.1421835983 3SE9 4I3R 4I3S 3J5M
VRC-PG04bDonor 74CD4bs7164 NA21835983NA
VRC-PG20IAVI 23CD4bs0.77 NA NA23911655 4LAJ 4LSU
VRC01Donor 45CD4bs93890.32 20616233 3NGB 4LSS 4LST
VRC02Donor 45CD4bs91880.1320616233NA
VRC03Donor 45CD4bs57480.2720616233 3SE8
VRC07Donor 45CD4bs97? NA25142607 4OLU
VRC23127/CCD4bs2.7 NA NA23661761 4J6R
Z13FDA-2gp41 MPER NA NA NA11602729NA

* Percent viruses neutralized with an IC50 < 50 μg/mg
** Percent viruses neutralized with an IC80 < 50 μg/mg

Key/Legend for Neutralization Breadth
Color Description
Neutralization > 90%
90% >= Neutralization > 60%
60% >= Neutralization > 30%
Neutralization < 30%
Neutralization data is not available in bNAber database
Key/Legend for Neutralization Potency
Color Description
Potency < 0.2 μg/ml
0.2 μg/ml <=Potency < 2 μg/ml
2 μg/ml <= Potency < 20 μg/ml
Potency data is not available in bNAber database