New videos demonstrating the latest analysis and visualization tools are now available! These initial videos are a walkthrough of the powerful new tools which have been developed in the Neutralization workbench tool or "Neutbench". You can watch the latest videos here.
New Polyreactivity and Sequence Data Available!
New, recently published bNAb data, such as polyreactivity, light and heavy v, j, and d region data is now available for most bNAbs! You can see this new data on the details page for each individual bNAb, such as PGT121.
Two newly discovered broadly neutralizing antibodies (bNAbs) have been deposited into the bNAber database. PGT151 and PGT152, both found to bind to the gp41 and gp120 interface residues and glycans, which appear to be a previously undefined target on the HIV envelope. The availability of this set of antibodies expands the number of vaccine targets on HIV and provides reagents to characterize the native envelope spike. This work was published in Immunity in April 2014, and can be found here.
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bNAber is a database, analysis, visualization, and data discovery tool for broadly neutralizing HIV-1 antibodies (bNAbs), and seeks to be a vital tool in the search for an AIDS vaccine.